Infectious Diseases
Reports Summarize Infectious Diseases Study Results from Erasmus University Medical Center
Published in Vaccine Weekly, February 22nd, 2012
2012 FEB 22 -- "Vibrio cholerae excreted by cholera patients is 'hyperinfectious'' ( HI), which can be modeled by passage through infant mice. Immunization of adult female mice with V. cholerae outer-membrane vesicles (OMVs) passively protects suckling mice from challenge. Although V. cholerae is unable to colonize protected pups, the bacteria survive passage and have the potential to be transmitted to susceptible individuals," scientists in Rotterdam, Netherlands report.
"Here, we investigated the impact of OMV immunization and the HI state on V. cholerae transmission. Neonatal mice suckled by OMV- or sham-immunized dams were challenged with HI V....
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Source: Vaccine Weekly (2012-02-22)
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