T-Lymphocyte Antigens
Researchers from University of Southampton Detail Findings in T-Lymphocyte Antigens
Published in Vaccine Weekly, February 22nd, 2012
2012 FEB 22 -- According to the authors of a study from Southampton, United Kingdom, "A major contributing factor to the final magnitude and breadth of CD8+ T-cell responses to complex antigens is immunodomination, where CD8+ T cells recognizing their cognate ligand inhibit the proliferation of other CD8+ T cells engaged with the same APC. In this study, we examined how the half-life of cell surface peptideMHC class I complexes influences this phenomenon."
"We found that primary CD8+ T-cell responses to DNA vaccines in mice are shaped by competition among responding CD8+ T cells for nonspecific stimuli early after activation and prior to cell division. The...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
Source: Vaccine Weekly (2012-02-22)
More Articles from Vaccine Weekly
- Physiology
University of Tubingen Reports Research in Physiology - Vaccines
University of Tennessee College of Medicine Reports Research in Vaccines - Staphylococcus aureus
University of Reading Reports Research in Staphylococcus aureus - Salmonella
University of Birmingham Details Research in Salmonella - Influenza Vaccines
University of Maryland School of Medicine Details Research in Influenza Vaccines - Vaccines
The Valley Hospital in Ridgewood, NJ, Now Participating in a Clinical Trial Studying Personalized Vaccine for Treating a Common Form of Brain Tumor - More from this issue of Vaccine Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
