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Tuberculosis

Research from Queen Mary University Yields New Findings on Tuberculosis

Published in Vaccine Weekly, March 7th, 2012

2012 MAR 7 -- "Neutrophils are rapidly recruited to sites of mycobacterial infection, where they phagocytose bacilli. Whether neutrophils can kill mycobacteria in vivo probably depends on the tissue microenvironment, stage of infection, individual host, and infecting organism," scientists writing in the journal Trends in Immunology report.

"The interaction of neutrophils with macrophages, as well as the downstream effects on T cell activity, could result in a range of outcomes from early clearance of infection to dissemination of viable bacteria together with an attenuated acquired immune response. In established disease, neutrophils accumulate in...

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