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Study Findings from GlaxoSmithKline Provide New Insights into Vaccines

Published in Vaccine Weekly, March 14th, 2012

2012 MAR 14 -- According to the authors of recent research published in the journal Clinical and Vaccine Immunology, "Influenza A/H3N2 viruses have caused the most severe epidemics since 1968 despite current immunization programs with inactivated vaccines. We undertook a side-by-side preclinical evaluation of different adjuvants (Alum, AS03, and Protollin) and routes of administration (intramuscular [i.m.] and intranasal [i.n.]) for assessing their effect on the immunogenicity and cross-reactivity of inactivated split vaccines (A/H3N2/New York/55/2004)."

"Humoral and T cell-mediated immune responses against the homologous virus and a heterologous...

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