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DNA Research

New DNA Research Research Has Been Reported by Scientists at University of Ottawa

Published in Vaccine Weekly, April 11th, 2012

2012 APR 11 -- New research, "Electrochemical differentiation of epitope-specific aptamers," is the subject of a report. "DNA aptamers are promising immunoshielding agents that could protect oncolytic viruses (OVs) from neutralizing antibodies (nAbs) and increase the efficiency of cancer treatment. In the present Article, we introduce a novel technology for electrochemical differentiation of epitope-specific aptamers (eDEA) without selecting aptamers against individual antigenic determinants," scientists in Ottawa, Canada report.

"For this purpose, we selected DNA aptamers that can bind noncovalently to an intact oncolytic virus, vaccinia virus (VACV),...

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