2012 MAY 9 -- Research findings, "Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony stimulating factor (GM-CSF): II. Adverse effects of GM-CSF," are discussed in a new report. According to the authors of a study from Prague, Czech Republic, "Granulocyte-macrophage colony stimulating factor (GM-CSF) is considered to be the most effective immunostimulating factor for the construction of gene-engineered anti-cancer vaccines. In some tumor cells, this type of genetic modification has resulted in the loss of the oncogenic potential."
"This was not the case with bcr-abl-transformed mouse 12B1...
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