Published in Virus Weekly, October 17th, 2000
"Visualization of antigen-specific T cells has become an important tool in studying immune responses," stated V. Grosse and colleagues. "The aim of this study was to analyze CMV-specific CD4+ T cells in healthy and HIV infected individuals."
The researchers examined peripheral blood mononuclear cells (PBMC) for antigen-induced intracellular cytokine responses. They detected significant numbers of CMV-specific CD4+ T cells in most CMV-immunoglobulin G (IgG+) HIV-1 infected individuals, but did not...
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