Oral Cancer

Human papillomavirus infection is a prognostic factor for disease and outcome

Published in Virus Weekly, April 29th, 2003

Men have a higher risk of papillomavirus-reactive oral carcinomas; risk was higher for oral sex practice and lower for smoking, and overall survival was better for those who had infected than noninfected cancers.

"Although studies have established human papillomaviruses (HPVs) as a risk factor for oral and oropharyngeal cancer, it is not clear whether viral infection affects survival in head and neck malignancies.

"This investigation examined the relationship between HPV and survival in carcinomas of the oral cavity and oropharynx. Formalin fixed, paraffin embedded tumor specimens from 139 newly diagnosed cases were tested for HPVs by PCR and DNA...

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Source: Virus Weekly (2003-04-29)

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