Viral Genomics
Duck hepatitis B virus core protein contains a central site for genome release
Published in Virus Weekly, September 9th, 2003
"Viral nucleocapsids compartmentalize and protect viral genomes during assembly while they mediate targeted genome release during viral infection. This dual role of the capsid in the viral life cycle must be tightly regulated to ensure efficient virus spread. Here, we used the duck hepatitis B virus ( DHBV) infection model to analyze the effects of capsid phosphorylation and hydrogen bond formation," researchers in Germany report.
"The potential key phosphorylation site at serine 245 within the core protein, the building block of DHBV capsids, was substituted by alanine...
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Source: Virus Weekly (2003-09-09)
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