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Virus Weekly

Susan Hasty, Publisher

Table of Contents . . . November 2nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Virus Weekly | Other Publications

Cardiac Virus Detection - Real-time PCR is an efficient method to detect PVB19 infection in heart tissue

Epstein Barr Virus - EBV is integrated between REL and BCL-11A in American Burkitt lymphoma cell line

Influenza Virus - Influenza B virus lacks sequence homology to influenza A virus antigenic sites

Lentivirus - LEDGF/p75 is a component of functional lentiviral preintegration complexes

SARS Coronavirus - Highly infectious SARS-CoV reveals cell tropism/receptor expression correlation

AIDS/HIV Diagnosis - HIV-1 superinfections assessed by autologous heteroduplex mobility

Adenovirus - Membrane Cofactor Protein identified as adenovirus receptor

Animal-Borne Disease - New laboratory provides key research into animal diseases

Antisense Technology - Antisense inhibitors of TRADD could modulate TNF-related pathologies

Antiviral Therapy - RANTES haplotypes influence the response to chronic hepatitis C therapy

Avian Influenza Vaccine - Reassortant influenza vaccines control avian influenza

Cancer Risk Factor - Hepatitis B virus core promoter mutations prevail in liver cancer

Cancer Vaccine - Raf kinase expression increases mortality of influenza-infected mice

Cervical Cancer - Infection site and patient ethnicity affect HPV-induced cancer pathways

Chronic Hepatitis B - Estrogen receptor alpha genotypes associate with susceptibility to hepatitis B

Chronic Hepatitis B - Lamivudine does not improve the response of hepatitis B to peginterferon

Chronic Hepatitis B - Real-time PCR and melting curve analysis offer rapid assessments of hepatitis B

Chronic Liver Disease - Serum hepatitis B virus strains parallel hepatic strains in acute exacerbations

Chronic Liver Disease - Site-specific keratin hyperphosphorylation marks liver disease progression

Circovirus Type 2 - Porcine circovirus type 2 from pigs was in Croatia detected and characterized

Cirrhosis - Epivir-HBV delays liver complications from chronic hepatitis B

Collaborations - Agreement signed to market docosanol 10% cream in Scandanavia

Conjunctivitis Outbreak - E-mail surveys assist investigation and response in conjunctivitis outbreak

Cytomegalovirus Vaccine - Microneutralization assay using cytomegalovirus strains developed

DNA Research - Viral DNA damage in presence of RB, UV light may make normal repair less likely

Diagnostic Devices - HIV diagnostic proves effective in Dominican Republic trials

Diagnostics - Chinese CDC attends HIV/AIDS training seminar

Diagnostics - Total HCV core antigen assay detects early infection but not viral elimination

Disease Associations - Immune restoration disease arises in association with antiretroviral therapy

Disease Transmission - Older women's knowledge of HIV is lacking, study finds

Drug Development - Inhalation drug company secures new funding

Drug Development - Novel antiapoptotic protein X-linked IAP antagonists potential cancer therapy

Drug Development - Novel compounds exhibit antiviral and antitumor effects

Encephalitis Vaccine - Ascorbate-Cu(II) protects CF-1 mice against HSV-2 encephalitis

Finance - Diagnostics firm secured new funding to develop new sensor technology

Foot and Mouth Disease - ELISA to detect foot-and-mouth disease virus antibodies developed

Genomics - Comparative study of Legionnaire's disease published

Group B Rotaviruses - Group B rotaviruses have been circulating in Western India since 1993

HIV/AIDS - Biopharma company intends to continue development of treatment for Cachexia

HIV/AIDS Epidemiology - HIV-1 non-B subtypes from heterosexual transmission predominate in Scotland

HIV/AIDS Prevention - New lead in quest to protect women from sexual HIV transmission

HIV/AIDS Prevention - Peer program teaches inmates about HIV/AIDS

HIV/AIDS Research - APOBEC3G incorporated into HIV-1 virions through viral/nonviral RNA interactions

HIV/AIDS Research - Antisense U7 snRNAs and siRNAs targeting cyclophilin A inhibit HIV-1 replication

HIV/AIDS Research - Dying cells drive the capacity of HIV-1 to kill noncycling primary CD4+ cells

HIV/AIDS Research - HIV-1 infectivity enhanced by forming particle-mediated syncytia in CD4+ cells

HIV/AIDS Research - Host cell gene expression varies during HIV-1 latency or reactivation

HIV/AIDS Research - Memantine protects hippocampal neuronal function in HIV-1 encephalitis

HIV/AIDS Research - R5 HIV-1 replicates more efficiently in primary CD4+ cells than X4 HIV-1

HIV/AIDS Research - Structure of initiation complex of HIV-1 reverse transcription is not conserved

HIV/AIDS Research - TSG101 mutations that inhibit PTAP or VPS28 binding block HIV-1 budding

HIV/AIDS Research - Tumorigenesis by HHV-8 chemokine receptor vGPCR is accelerated by HIV-1 Tat

HIV/AIDS Therapy - CD4+ cell non-production during HAART due to inefficiencies at multiple steps

HIV/AIDS Therapy - Jury is still out regarding benefits of switching to protease-sparing regimen

HIV/AIDS Therapy - Nevirapine is better than efavirenz at raising "good" cholesterol

HIV/AIDS Treatment - Former Maryland Governor wants public registry for people with AIDS

HIV/AIDS Treatment - HIV-positive Russians detained during protest in western city

HIV/AIDS Vaccine - CCR5-targeted SIV vaccination strategy prevents or inhibits SIV

HIV/AIDS-Related Pain Medicine - HIV-1 gp120-induced nitric oxide increases proinflammatory cytokines

Healthcare Coverage - Health workers confirm Wisconsin's first flu case of the season

Hematology - A new magnetic extraction method uncovers HCV status in hemodialysis patients

Hepatitis - Drug development company announces hepatitis C study presented at conference

Hepatitis - Study reports results of PegIntron and Rebetol combination therapy for hepatitis

Hepatitis B Virus - Abstract describing remofovir study results posted to AASLD web site

Hepatitis C Virus Infection - Persistence of hepatitis C virus associated with human leukocyte antigen class 1

Hepatitis/HIV Coinfection - FDA grants priority review to Pegasys with Copegus for HCV in HIV patients

Hepatology - Novel peptide-based vaccines generate immunity to hepatotropic pathogens

Hepatology - Patients with liver disease have lower levels of circulating dendritic cells

Herpesvirus Vaccine - Viral subunit protein plus CpG ODN protects against HSV-2

Human Papillomavirus Vaccine - HPV type 18 L1 VLP vaccine safe and immunogenic in women

Immunology - Dendritic cells in chronic hepatitis C patients alter immunological response

Infection Control - Disinfection, and sterilization adherence reduce hospital-related infections

Influenza - Bacterium causes U.S. flu vaccine shortage

Influenza - Disease management company to offer viral antidote to U.S. during flu season

Influenza - Drug-DNA combination could offer longer-lasting, more efficient flu vaccine

Influenza - Experts: Good hygiene can ward off flu

Influenza - Study to test flu shot and nasal spray flu vaccine side by side

Influenza - Survey of hospitals quantifies flu vaccine price gouging

Influenza - U.S. CDC urges high-risk groups to get vaccinated, healthy people to wait

Influenza Vaccine - Cost of flu vaccine rising as supply dwindles

Influenza Vaccine - Effect of influenza vaccination on primary care contact rates studied

Influenza Vaccine - Remaining flu shots directed to high-risk patients

Influenza Vaccine - Study of influenza virus A M2 peptide conjugate vaccines conducted

Influenza Virus - Antigenically and genetically similar influenza C viruses in Japan characterized

International Collaborations - Scientists meet to work on strategy to fight global viruses

Legal Issues - Judge says Nebraska liable for bulk of any successful hepatitis lawsuits

Liver Cancer - Patients with hepatic fibrosis and hepatitis C need broader cancer screenings

Mutagenesis - PCR-RFLP is quick and reliable for detecting hepatitis B virus core mutants

Oncolysis - Viral properties can be incorporated into adenovirus-based cancer therapies

Papillomatosis - Omomyc expression in the skin prevents Myc-induced papillomatosis

Parainfluenza Virus - Sendai virus vaccine is safe and immunogenic in healthy adults

Polio Vaccine - Polio vaccines containing simian virus 40 may cause human cancer

Poxvirus Vaccine - Structural proteomics of the poxvirus family reviewed

Respiratory Syncytial Virus - HLA-DP4 presents immunodominant peptide from RSV G protein to T cells

SARS Infection Control - Providing SARS infection control information to outpatients increases compliance

SARS Vaccine - Antibody responses against SARS-coronavirus studied in SARS patients

Sexually Transmitted Disease - Interactive video behavioral intervention reduces adolescent females' STD risk

Smallpox - FDA fast track status granted for modified vaccinia ankara program

Smallpox - U.S. HHS awards $232 million in biodefense contracts for vaccine development

Smallpox Research - California scientists help bring study of smallpox virus into 'molecular age'

Smallpox Vaccine - Positive side effects of smallpox vaccination described

Swine Fever Virus - Optimized protocol developed for detection of classical swine fever virus

Transplantation Medicine - Newer drugs target recurrent hepatitis B after liver transplantation

Tumorigenesis - IKK beta links inflammation and tumorigenesis in colitis-associated cancer

Usutu Virus - Pathology/viral distribution characterized in fatal usutu virus infection

Vaccine Adjuvant - CPG 7909 allows lower dose of Fluarix influenza vaccine

Vaccine Development - Novel vaccine containing hepatitis C E1 protein shows promise in volunteers

Vaccine Vector - Adenoviral vector carrying type 35 fiber is promising vaccine vehicle

Vaccines - Flu vaccine distribution to follow CDC guidelines

Vaccines - Study finds demand for vaccines in U.S. will increase 8.6% annually

Vector Development - Influenza A virus hemagglutinin constructs tend to lose fusion activity

Viral Hepatitis - Hepatitis B superinfection cannot restore hepatitis C-specific CD8 reactivity

Virology - Estimates of hepatitis E virus mutagenesis produce alluring data

Virology - Host immunology and genomics govern hepatitis C virus progression

Virology - Poxvirus protein N1L inhibits NF-kappa B and IRF3 signaling

Virology Vaccine - Interfering vaccine converts virulent infection into immunizing one

Virology Vaccine - PRRSV vaccine did not affect virus shedding in PRRSV-infected pigs

West Nile Fever - Clinicopathologic study of West Nile Virus encephalomyelitis reported

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