Antiviral Drug Development
Rab9 identified as a novel antiviral drug target
Published in Virus Weekly, November 23rd, 2004
"Rab GTPases and their effectors facilitate vesicular transport by tethering donor vesicles to their respective target membranes.
"Rab9 mediates late endosome to trans-Golgi transport and has recently been found to be a key cellular component for human immunodeficiency virus-1, Ebola, Marburg, and measles virus replication, suggesting that it may be a novel target in the development of broad spectrum antiviral drugs," scientists in the United States report.
"As part of our structure-based drug design program," said L.Q. Chen and coworkers, "we have determined the crystal...
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Source: Virus Weekly (2004-11-23)
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