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Virus Weekly

Susan Hasty, Publisher

Table of Contents . . . April 5th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Virus Weekly | Other Publications

Allergy and Immunology - Immunomodulatory therapy for chronic hepatitis B prevents liver complications

HIV/AIDS Vaccine - C-terminal tail of HIV transmembrane glycoprotein involved in cell fusion

Hepatitis C Therapy - Chronic hepatitis C resolves following antiviral treatment and relapse

Herpes Simplex Virus Type 1 - Differences between sexes in HSV-1 infection and disease studied

SARS - Convalescent plasma therapy shortens hospitalization stays of SARS patients

Adverse Drug Reaction - Rituximab ameliorates interferon-related thrombocytopenia

Amyotrophic Lateral Sclerosis - Researchers detail new studies and findings in the area of amyotrophic lateral sclerosis

Antiviral Therapy - Acylated peptides battle hepatitis B virus infection

Avian Influenza - Cross-impact analysis predicts mutation trends in influenza A

Borna Disease - Orf virus protects against Borna disease virus infection of the brain

Bovine Viral Diarrhea Virus - Genome analysis of live bovine viral diarrhea virus vaccine conducted

Virology - Recent findings illuminate research in virology

Cancer Drugs - Adult T-cell leukemia lymphoma cells displayed sensitivity to TRAIL

Cervical Cancer - L1 sequence of a new human papillomavirus associated with cervical cancer

Cervical Cancer - Most women willing to accept vaccine for self and children

Cervical Cancer - PML-induced senescence circumvented by human papillomaviruses

Chronic Liver Disease - Hepatitis C virus and oxidative stress constitutively activate STAT-3

Colon Cancer - Gene replacement therapy suppresses colorectal tumors in animal models

Virology - Researchers' findings advance virology research

Cowpox - Cowpox virus infection associated with streptococcal septicemia

Crimean-Congo Hemorrhagic Fever - ELISA method used to diagnose Crimean-Congo hemorrhagic fever

Cytomegalovirus Vaccine - Cytomegalovirus DNA vaccine protects against murine cytomegalovirus challenge

Dengue Hemorrhagic Fever - Dengue hemorrhagic fever increasing among children in northern Brazil

Dengue Virus - Effect of DEN-2 infection on macrophage gene expression determined

Diagnostics - Data advance knowledge in diagnostics research

Virology - Studies advance knowledge in virology research

Dilated Cardiomyopathy - Dilated cardiomyopathy requires immunohistochemical and molecular investigation

Disease Associations - Epstein-Barr LMP2A and LMP2B studied, effect on epithelial cells noted

Drug Development - Hepatitis C replicons enhance our ability to develop new antivirals

Environmental Health - Reverse transcription-PCR detects hepatitis A in spring water

Environmental Health - Study of microbes living in air is funded by $2.5 million Alfred P. Sloan grant

Equine Infectious Anemia Virus - Specificity of antibodies induced by equine infectious anemia virus reported

Virology - Studies describe new findings in virology research

Finance - Anti-infectives-focused biotech company announces $5.5 million rights offering

Finance - Biotech company receives going concern qualification in FY2004 audit report

HIV/AIDS - Styrylquinolines are synergistic with other antiretroviral agents

HIV/AIDS Drug Development - Anti-HIV-1 compounds separated via capillary zone electrophoresis

HIV/AIDS Drug Development - PNA-transportan conjugate targeted to HIV-1 TAR is antiviral and virucidal

HIV/AIDS Drug Development - Plant extracts have anti-HIV activity

HIV/AIDS Drug Discovery - HIV-1 integrase inhibitors identified using 3D pharmacophore-guided database

HIV/AIDS Drug Resistance - Drug-resistant HIV-1 genotypes detected only in subjects infected after 2000

HIV/AIDS Drug Resistance - HIV-1 Vif changes associated with development of protease inhibitor resistance

HIV/AIDS Infection - Amphotericin-B reactivates latent HIV-1 infection

HIV/AIDS Lipodystrophy - VLDL elevation in early HAART therapy caused by impaired VLDL clearance

HIV/AIDS MALT Lymphoma - HIV+ MALT lymphoma remission induced by HAART alone

HIV/AIDS Pathogenesis - APOBEC3G polymorphisms not associated with HIV disease progression

HIV/AIDS Pathogenesis - C-terminal domain of HIV-1 integrase is a DNA-binding domain

HIV/AIDS Pathogenesis - Cytoplasmic tail slows HIV-1 Env folding from late prebundle into 6-helix bundle

HIV/AIDS Pathogenesis - Late stage R5 HIV-1 infection induces cytokine and CCR5 expression

HIV/AIDS Pathogenesis - M-tropic HIV-1 activation increases virus load in intestinal mucosa

HIV/AIDS Pathogenesis - Separate HIV Nef domains are required to affect MHC-1 and CD4 cells

HIV/AIDS Pathogenesis - Vpr enhances RANKL production via glucocorticoid receptor activity potentiation

HIV/AIDS Prevention - Manufacturing company wins government tender for rapid HIV test in China

HIV/AIDS Prognosis - Survival prognostic factors differ by CD4 count among IVDU pre/post HAART era

HIV/AIDS Research - CD4+ cell response differs between HIV-exposed seronegative and HIV+ women

HIV/AIDS Research - MLV RNase H primer grip is an important determinant of fidelity of DNA synthesis

HIV/AIDS Research - Tat methylation by PRMT6 regulates HIV-1 gene expression

HIV/AIDS Screening - Molecular diagnostics company reports detection of HIV-DNA AIDS patients' urine

HIV/AIDS Screening - Urgent care center-based routine HIV screening programs are effective

HIV/AIDS Therapy - 20 mg/kg of amprenavir twice daily is safe for HIV-infected children

HIV/AIDS Therapy - C/EBP alpha reverses anti-adipogenic effects of nelfinavir

HIV/AIDS Therapy - Encouraging results reported from phase 2 trial of HIV immune-based therapy

HIV/AIDS Therapy - Fixed conformation nucleoside analogs inhibit excision-proficient HIV-1 RT

HIV/AIDS Therapy - HAART leads to normalization of anti-Hsp70 and anti-cholesterol Ab levels

HIV/AIDS Therapy - IL-16 levels increase after structured intermittent HAART interruption

HIV/AIDS Therapy - Researchers' work adds to HIV/AIDS therapy body of knowledge

HIV/AIDS Therapy - Ritonavir does not inhibit calpain

HIV/AIDS Vaccine - Anti-CXCR4 antibodies differ significantly in ability to inhibit HIV entry

HIV/AIDS Vaccine - HIV preventive vaccine trials in developing countries examined

HIV/AIDS Vaccine - Peptide immunogens enhance immune response against HIV mutant strains

HIV/AIDS Vaccine - Poxvirus SIV vaccine partially protects juvenile macaques against SIV

HIV/AIDS Vaccine - Predictive value of primate models for AIDS therapies reviewed

HIV/AIDS Vaccine - Rhabdoviral prime-boost induces strong anti-HIV immune responses

HIV/AIDS Vaccine - Role of IL-7 in pathogenesis and treatment of HIV infection reviewed

HIV/AIDS Vaccine - Targeting CD4i epitope in HIV vaccine design explored

HIV/AIDS-Associated Lipodystrophy - Subcutaneous fat loss not due to accelerated apoptosis in HIV lipodystrophy

Hepatitis B Therapy - Hepatitis B virus genotypes direct therapeutic response

Human Papillomavirus - Epitope specificity of vaccine-induced T cell response against HPV18 reported

Human Papillomavirus - HPV-13 polymorphisms determined for HIV+ and women at risk for HIV infection

Human Papillomavirus - New research targets men to study virus that causes cancer in women

Infections - Inflammatory and antiviral responses in liver studied, requirements clarified

Influenza - Pharmaceutical company launches new version of its pediatric influenza vaccine

Influenza - Role of fetal and maternal cells in antiviral defense probed

Influenza Vaccine - Acidic polymerase epitope of influenza elicits potent antiviral response

Influenza Vaccine - Approaches to influenza prevention and treatment in travelers reviewed

Influenza Vaccine - Growth of attenuated influenza vaccine strains in cell lines achieved

Influenza Vaccine - Safety and immunogenicity of adenovirus-vectored influenza vaccines reviewed

Influenza Vaccines - Findings describe new data in influenza vaccines research

Kaposi Sarcoma-Associated Herpesvirus - New findings in the area of kaposi sarcoma-associated herpesvirus described

Lipid Studies - Serum lipoprotein(a) levels decline in patients with viral hepatitis

Marketing - Company launching direct-to-consumer advertisements for HPV test

Measles Vaccine - Impact of population decline on dynamics of measles in Italy explored

Mergers & Acquisitions - Shareholders of pharmaceuticals companies approve merger

Norovirus - New data illuminates research in norovirus

Oncology - Studies add new findings to oncology body of knowledge

Patents - RNA interference-based therapeutics company granted patent

Pediatrics - Pediatric nurse group alerts parents to dangers of rotavirus infection

Polio Vaccines - Researchers' work adds to polio vaccines body of knowledge

Progressive Multifocal Leukoencephalopathy - Novel monoclonal antibody inhibits JC virus cell entry

Respiratory Pathogen - Respiratory infection spread during air travel rarely occurs

Retroviruses - Env disulfide bond isornerase examined, nature of triggering clarified

Rotavirus Vaccine - Immunization with rotavirus virus-like particles elicits immune responses

Rotavirus Vaccines - Researchers detail new studies and findings in the area of rotavirus vaccines

SARS - Events reconstructed during SARS outbreak in February 2003 in Singapore

SARS - Novel monoclonal antibodies neutralize SARS coronavirus in vitro

SARS - Nursing students more stressed than medical students during SARS outbreak

SARS - SARS seroprevalence rate is low in apparently healthy healthcare workers

SARS - SARS spike membrane glycoprotein studied, membrane active regions revealed

SARS Coronavirus - Recombinant nucleocapsid protein-based assay detects anti-SARS-CoV IgG

SARS Coronavirus - Researchers report details of new studies and findings in the area of SARS coronavirus

SARS Prevention - Residents of Taiwan have increased "willingness to pay" to reduce SARS risk

SARS Vaccine - Two neutralizing regions on SARS spike glycoprotein identified

SARS Virus - Hamster is better model than mouse for therapy against SARS virus replication

SARS Virus - SARS clinical features in the United States described

Transplant Medicine - Unexplained hepatitis in renal graft recipients may be caused by hepatitis E

Tuberculosis - String test as sensitive as sputum induction for TB detection in HIV infection

Vaccine Development - Nanoparticle-based immunization challenges hepatitis B virus infection

Vector Development - Inorganic phosphate nanoparticles support efficient pDNA transfection

Virology - 'Shooting galleries' spawn the transmission of infectious diseases

Virology - Apoptosis markers trace histological activity in viral hepatitis patients

Virology - Assembly polymerase chain reaction builds near full-length HCV cDNA clones

Virology - Clonal expansion accompanies woodchuck hepatitis virus infection

Virology - Findings describe new data in virology research

Virology - Hepatitis C virus genotype distribution varies in Brazil

Virology - Herpes simplex virus infection studied, endoplasmic reticulum effects clarified

Virology - MHC class molecules studied, complex with influenza virus epitopes revealed

Virology - Norovirus transmission documented on cruise ship

West Nile Virus - Interferon can cure cells of West Nile virus replicons

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