Virus Weekly

Cancer Therapy - Collaboration invents "virus in stealth" to help kill cancer cells

HAM/TSP Pathogenesis - Interferon-beta 1a affects immune mechanisms central to HAM/TSP pathogenesis

HIV/AIDS Opportunistic Infection - Calciviruses may be important opportunistic pathogen in HIV-infected children

Liver Cancer - Researchers discover link between viral infection and liver cancer

Smallpox Vaccine - Stable/effective smallpox vaccine constructed from highly attenuated vaccinia

Addiction Medicine - Daily marijuana use exacerbates chronic hepatitis C-related liver fibrosis

Adverse Drug Reaction - Advance liver disease hampers tolerance to hepatitis C combination therapy

Asthma - Omalizumab add-on therapy reduced severe allergic asthma attacks in 7 studies

Awards - Stephen C. Harrison wins Bristol-Myers Squibb infectious diseases research award

Business & Finance - Diagnostic tests company projects first quarter profit

Business Update - Human Genome Sciences announces financial results for second quarter of 2005

HIV/AIDS Vaccines - New research in the area of HIV/AIDS vaccines detailed

Cancer Therapy - Patient enrollment completed in REOLYSIN clinical trial for cancer treatment

Cancer Vaccines - Findings describe new data in cancer vaccines research

Cardiology - Human cytomegalovirus activates signals that trigger neointimal proliferation

Chronic Hepatitis B - Liver disease severity beats hepatitis B genotype as a cause of drug resistance

Chronic Hepatitis C - Hepatitis C genotype 4 is highly insensitive to pegylated interferon

Chronic Liver Disease - Apparent diffusion coefficient measurements help stage liver fibrosis

HIV/AIDS Vaccines - Researchers detail new studies and findings in the area of HIV/AIDS vaccines

Chronic Liver Disease - Hepatitis B cirrhosis-related complications arise despite low DNA levels

Cidofovir - Cidofovir treated recurrent respiratory papillomatosis

Clinical Trials - Eight-week doxycycline course safe/effective for lymphatic filariasis

Cytomegalovirus - CMV-specific cytotoxic T cells expanded using recombinant polyepitope

DNA Vaccine - Adenovirus purification process developed using DNA precipitation

DNA Vaccine - Role of particle-mediated DNA vaccines in biodefense reviewed

HIV/AIDS Vaccines - Researchers provide details of new studies and findings in the area of HIV/AIDS vaccines

Diagnostics - HPV genotyping can benefit clinical practice, study concludes

Diagnostics - Immunoglobulin avidity clarifies the diagnosis of hepatitis A

Diagnostics - Minisequencing and mass spectrometry uncover hepatitis C genotypes

Diagnostics - Recent studies add new data to diagnostics research

Disease Associations - SARS studied, response of memory CD8+ T cells revealed

Drug Discovery - Antibacterial and antiviral peptide isolated from soya beans described

HIV/AIDS Vaccines - Researchers publish new studies and findings in the area of HIV/AIDS vaccines

Drug Resistance - Cytomegalovirus drug resistance mutations phenotyped

Enzymology - Recent findings in enzymology provide new insights

Epidemiology - Combined genetic polymorphisms encourage chronic hepatitis C progression

Epstein-Barr Virus - Researchers detail new studies and findings in the area of epstein-barr virus

Epstein-Barr Virus - SM protein enhances expression of Epstein-Barr virus lytic genes

Finance - Health products company reports second quarter results

Proteomics - Researchers report details of new studies and findings in the area of proteomics

Finance - Infections-focused biotechnology company reports second quarter 2005 results

Finance - Molecular diagnostics company reports second quarter 2005 financial results

Gene Research - Interleukin-10 variations influence immune response to hepatitis vaccine

Gene Therapy - Adeno-associated virus vectors in central nervous system reviewed

Genital Herpesvirus Infection - Topical microbicides needed for prevention of genital herpes infections

HIV/AIDS Coinfection -  Neisseria gonorrhoeae enhances infection of dendritic cells by HIV-1

SARS Vaccines - Studies describe new findings in SARS vaccines research

HIV/AIDS Diagnosis - Ten-minute, U.S. FDA-approved HIV test developed

HIV/AIDS Disease Progression Risk Factors - Pattern/type of non-injection drug use associated with progression to AIDS

HIV/AIDS Drug Development - Amino acid Asn136 of HIV-1 RT enables rational design of RT inhibitors

HIV/AIDS Drug Development - Mesuol inhibits HIV-1 replication by targeting NF-kappa B pathway

HIV/AIDS Drug Development - Short hairpin RNAs targeting human cyclin T1 suppresses HIV-1 replication

HIV/AIDS Education - Low health literacy associated with HIV test acceptance

Virology - Findings advance knowledge in virology research

HIV/AIDS Education - Peer education or lecture increases HIV/AIDS knowledge among college students

HIV/AIDS Epidemiology - Differential susceptibility important determinant of steady-state HIV prevalence

HIV/AIDS Epidemiology - Majority of HIV-1 cases among Africa-born patients in Minnesota are non-B

HIV/AIDS Needlestick Injury - Postexposure practice inadequate in medical students with needlestick injury

HIV/AIDS Pathogenesis - CD4+ cells have impaired base excision repair/oxidative base lesion accumulation

HIV/AIDS Pathogenesis - Cultured myeloid dendritic cells from HIV patients fail to differentiate

Virology - Researchers' findings advance virology research

HIV/AIDS Pathogenesis - HIV Tat induction of IL-10 dysregulation associated with PKR activation

HIV/AIDS Pathogenesis - Infectivity of CXCR4-using isolates depends on CD4 expression

HIV/AIDS Pathogenesis - Peripheral S-phase T cells in HIV disease have a central memory phenotype

HIV/AIDS Pathogenesis - Reports describe recent advances in HIV/AIDS pathogenesis research

HIV/AIDS Perinatal Transmission - Nevirapine resistance after single NVP dose higher in women with HIV-1 subtype C

HIV/AIDS Pharmacokinetics - Body weight/female gender affects enfuvirtide clearance but not safety/efficacy

HIV/AIDS Prevention - HIV prevention program increases willingness to reduce adolescent risk behaviors

HIV/AIDS Prognostic Marker - Early HIV-1 PBMC DNA level predicts disease progression independent of RNA/CD4+

HIV/AIDS Research - CHMP offers positive opinion in Europe for Tipranavir

HIV/AIDS Research - Enrollment complete in phase 1 trial of PRO 140

HIV/AIDS Research - Phase IIb sudy shows Reverset trial results reported

HIV/AIDS Research - Single-chain antibody against HIV-1 external glycoprotein gp120 developed

HIV/AIDS Research - Soluble HIV trimeric Env fragment adopting prefusion gp41 structure developed

HIV/AIDS Risk Behavior - Adults with severe mental illness engage in risky sexual behaviors

HIV/AIDS Risk Behavior - Sexual risk behavior is high among youths in psychiatric care