Virus Weekly

Cervical Cancer - Examination E7 indicates pRb as important target in cervical cancer analysis

Epstein Barr Virus - Two distinct cells of origin for EBV-positive and EBV-negative Burkitt lymphomas

Oncology - Hepatitis B virus DNA alters genes near specific integration sites

Virology - Dengue virus NS1 studied, fate of secreted form defined

Adverse Drug Reaction - GSK makes changes to the development program for ONO-4128/873140

Adverse Drug Reaction - Interferon-induced mood disorder derives from overlapping conditions

Cancer Prevention - Lamivudine reduces cancer incidence in patients with chronic hepatitis B

Cancer Screening - The incidence of HPV-related cervical cancers increase in summer months

Cancer Therapy - Recent studies add new data to cancer therapy research

Cancer Vaccine - Interactions of anti-apoptotic proteins and TNF described

HIV/AIDS Vaccines - Studies add new findings to HIV/AIDS vaccines body of knowledge

Cardiology - Neurohormonal antagonism reverses hepatitis C-linked vascular remodeling

Cervial Cancer Risk Factors - Association of HPV infection with development of cervical neoplasia explored

Cervical Cancer - Cancer risk evaluated for HIV-infected women with abnormal cervical cytology

Cervical Cancer - Data advance knowledge in cervical cancer research

Cervical Cancer - Relationship between abnormal Pap test and HPV examined

Common Cold - Common cold myths addressed

Hepatitis B Therapy - New findings in the area of hepatitis b therapy detailed

Cytomegalovirus - Researchers publish new studies and findings in the area of cytomegalovirus

Cytomegalovirus Retinitis Prognosis - Detectable plasma CMV load at CMV retinitis diagnosis associated with mortality

Diabetes Complications - Recovery time from Bell palsy is longer for those with diabetes

Diagnostics - Alpha-smooth muscle actin helps evaluate hepatitis B virus-related fibrosis

Diagnostics - Fibrosis markers predict interferon effects in pediatric hepatitis B patients

Diagnostics - Human papilloma virus test increases cancer detection rate

Virology - Recent findings in virology described

Drug Development - Hepatitis C clinical trial launched in India

Drug Development - Lipophilic antifolate trimetrexate inhibits Trypanosoma cruzi

Drug Development - Monoclonal antibody combination neutralizes natural rabies virus variants

Endocrinology - Insulin resistance influences non-alcoholic fatty liver disease outcomes

Epidemiology - Ancestral infection and selection graph reconstruct host virus histories

Epidemiology - Early clinical features of West Nile virus infection are nonspecific

Virology - Recent findings in virology provide new insights

Epidemiology - Surveillance data suggest that preschoolers drive flu epidemics

Finance - Diabetes-, Alzheimer-focused company reports fiscal 2005 year end financial results

Foot-and-Mouth Disease Outbreaks - Foot-and-mouth disease virus variant responsible for recent outbreaks in India

Gastroenterology - Hepatitis C virus infection promotes the formation of gallstones

HIV/AIDS & Pulmonary Tuberculosis - HIV patients with nonhealing oral lesions should be screened for pulmonary TB

HIV/AIDS Complications - According to a study, autoimmune overload may damage HIV-infected brains

HIV/AIDS Diagnosis - Rapid HIV antibody assays for detecting recent seroconversion modified

HIV/AIDS Diagnostics - Dried blood spots used for molecular diagnosis and monitoring HIV-1 infection

HIV/AIDS Diagnostics - Genotypic assay detects all HIV-1 protease and reverse transcriptase subtypes

HIV/AIDS Diagnostics - Microchip CD4 counting method monitors HIV in resource-poor settings

HIV/AIDS Diagnostics - One-step test system quantifies mixed populations of drug-resistant HIV-1

HIV/AIDS Diagnostics - Viral infectivity is maintained by an RNA protection buffer

HIV/AIDS Drug Adherence - Integrated home-based care increases adherence to antiretroviral therapy

HIV/AIDS Drug Adherence - Low HAART adherence in adolescents associated with younger age and depression

HIV/AIDS Drug Development - HIV-1 maturation inhibitors inhibit cleavage of capsid precursor

HIV/AIDS Drug Development - HIV-1 protease BRET2 biosensor assay screens new protease inhibitors

HIV/AIDS Drug Development - Interferon-induced exonuclease ISG20 has antiviral activity against HIV-1

HIV/AIDS Drug Development - Orally bioavailable CCR5 antagonist inhibits HIV-1 replication

HIV/AIDS Epidemiology - HIV-1 group M isolates are 100-fold-more fit than group 0 or HIV-2 strains

HIV/AIDS HAART - Lower pretreatment HIV diversity associated with spontaneous viremia control

HIV/AIDS Pathogenesis - CD4+CD25+ regulatory T cells crucial in HIV infection

HIV/AIDS Pathogenesis - Clade-specific HIV-1 Tat proteins significantly modify viral gene expression

HIV/AIDS Pathogenesis - Equal recombination events occur when infecting macrophages and T cells

HIV/AIDS Pathogenesis - HIV-1 Gag can be monoubiquitinated in all domains

HIV/AIDS Pathogenesis - HIV-1 Gag-RNA interaction occurs at a perinuclear/centrosomal site

HIV/AIDS Pathogenesis - HIV-1 env V1, V2, V3 regions affect viral phenotype in isolate-dependent manner

HIV/AIDS Pathogenesis - HIV-1 gp120 induces COX-2 expression in neuroblastoma cells via NF-kappaB/AP-1

HIV/AIDS Pathogenesis - HIV-induced change in CD antigen expression disease specific/outcome independent

HIV/AIDS Pathogenesis - Heterologous L-domain sequences have various abilities to promote HIV-1 budding

HIV/AIDS Pathogenesis - Mucosal barrier greatly limits SIV infection of cervicovaginal tissues

HIV/AIDS Pathogenesis - Plasmacytoid dendritic cells and myeloid DCs differentially susceptible to HIV-1

HIV/AIDS Prevention - Findings advance knowledge in HIV/AIDS prevention research

HIV/AIDS Prevention - HAART suppresses HIV-1 RNA/not DNA in breast milk during pregnancy/postpartum

HIV/AIDS Prognosis - Low CD4 counts before HIV-1 seroconversion do not affect disease progression

HIV/AIDS Prognosis - Monte Carlo approach simulates within-host dynamics of HIV-1 infection

HIV/AIDS Prognostic Indicator - Cutaneous HIV manifestations predict underlying immune status

HIV/AIDS Research - Study of RPI-MN completed indicating effectiveness in drug resistant HIV

HIV/AIDS Research - There may be a new weapon in the battle against HIV - a small tropical frog

HIV/AIDS Reverse Transcriptase - HIV-1 RT interacts with the 3'-OH of the incoming dTTP substrate

HIV/AIDS Risk Factors - Sexual behaviors examined for HIV risk factors in mixed cohort of women