Published in Virus Weekly, May 23rd, 2006
"HCV core protein, expressed with a Semliki Forest virus replicon, self-assembles into HCV-LP at the endoplasmic reticulum (ER) membrane, providing an opportunity to study HCV assembly and morphogenesis by electron microscopy. This model was used to investigate whether the processing of the HCV core protein by the SPP is required for the HCV-LP assembly," wrote M. Aitgoug-Houlte and colleagues, University of Tours.
"Several mutants were designed as there are conflicting reports concerning...
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