Herpes Simplex Virus Type 2 Vaccine
Recombinant vesicular stomatitis virus vector immunogenic against HSV-2
Published in Virus Weekly, June 27th, 2006
According to recent research from the United States, "Recombinant vesicular stomatitis virus (rVSV) vectors offer an attractive approach for the induction of robust cellular and humoral immune responses directed against human pathogen target antigens.
"We evaluated rVSV vectors expressing full-length glycoprotein D (gD) from herpes simplex virus type 2 (HSV-2) in mice and guinea pigs for immunogenicity and protective efficacy against genital challenge with wild-type HSV-2."
"Robust Th1-polarized anti-gD...
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Source: Virus Weekly (2006-06-27)
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