Vector Development
Downstream processing of oncoretroviral and lentiviral vectors is reviewed
Published in Virus Weekly, June 27th, 2006
According to their review, "Retroviral vectors from both oncoretroviral and lentiviral origins have a great potential as gene delivery vehicles. A number of research groups have devoted considerable effort to the development of large-scale production strategies for retroviral vectors. However, the manufacturing of clinical-grade vectors for gene therapy, especially for in vivo applications, additionally requires scaleable purification strategies to remove the contaminants present in the harvested supernatants while preserving...
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Source: Virus Weekly (2006-06-27)
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