Published in Virus Weekly, September 12th, 2006
Study 1: According to recent research from France, lipid-mediated introduction of hepatitis B virus (HBV) capsids into nonsusceptible cells allows highly efficient replication and facilitates the study of early infection events.
"HBV is an enveloped DNA virus which is highly infectious in vivo. In vitro, only primary hepatocytes of humans and Tupaia belangeri or the novel HepaRG cell line are susceptible to HBV, but infection is inefficient and study of early infection events in single cells is unsatisfactory.
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