Published in Virus Weekly, November 14th, 2006
"Invasion of glial cells by the human polyomavirus, JC virus (JCV), leads to a rapidly progressing and uniformly fatal demyelinating disease known as progressive multifocal leukoencephalopathy. The endocytic trafficking steps used by JCV to invade cells and initiate infection are not known," wrote W. Querbes and colleagues, Brown University.
They continued, "We demonstrated that JCV infection was inhibited by dominant defective and constitutively active Rab5-GTPase mutants that...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Virus Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.