HIV/AIDS Therapy
Research on HIV/AIDS therapy discussed by scientists at University of Cambridge, Department of Pathology
Published in Virus Weekly, February 6th, 2007
Fresh data on HIV/AIDS are presented in the report "Structure-function analysis of the ribosomal frameshifting signal of two human immunodeficiency virus type 1 isolates with increased resistance to viral protease inhibitors." According to a study from Cambridge, the United Kingdom, "Expression of the pol-encoded proteins of human immunodeficiency virus type 1 (HIV-1) requires a programmed -1 ribosomal frameshift at the junction of the gag and pol coding sequences. Frameshifting takes place at a heptanucleotide slippery sequence, UUUUUUA, and is enhanced by a stimulatory RNA structure located immediately downstream."
"In patients undergoing viral protease (PR) inhibitor...
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Source: Virus Weekly (2007-02-06)
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