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Cancer Gene Therapy



Findings from University College in cancer gene therapy reported



April 10th, 2007

Researchers detail in "Inhibition of angiogenesis by a Semliki Forest virus vector expressing VEGFR-2 reduces tumour growth and metastasis in mice," new data in cancer gene therapy. According to recent research published in the journal Gene Therapy, "Inhibition of tumor angiogenesis has been shown to restrict primary tumor growth and metastatic spread. This study examines the active induction of immune responses against tumor endothelial cells following immunization with recombinant Semliki Forest virus (rSFV) particles encoding murine vascular endothelial growth factor receptor-2 (VEGFR-2)."

"This approach was tested in two murine tumor models, CT26 colon...


Source: Virus Weekly (2007-04-10)

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