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Gene Therapy
Reports from New York University, University Cancer Institute add new data to research in gene therapy
April 10th, 2007
Current study results from the report, "Inhibition of cellular 2'-5' oligoadenylate synthetase by the herpes simplex virus type 1 Us11 protein," have been published. According to recent research from the United States, "Among the many host genes induced by virus infection and interferon, the eIF2alpha protein kinase PKR and the 2'-5' oligoadenylate synthetase (OAS) are both activated by double-stranded RNA (dsRNA) produced in virus-infected cells. Furthermore, each is a critical component that independently acts to inhibit virus replication and thereby contributes to the establishment of an antiviral state." "As part of their tactics to foil host defense mechanisms,...
Source: Virus Weekly (2007-04-10)
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