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Virus Weekly

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Arthritis Therapy



Research results from University of California update understanding of arthritis therapy



April 10th, 2007

Research findings, "Antiviral gene expression in rheumatoid arthritis: role of IKKepsilon and interferon regulatory factor 3," are discussed in a new report. According to a study from the United States, "The rheumatoid synovium displays characteristics of Toll-like receptor (TLR) activation and antiviral gene expression, including production of RANTES and interferon-beta (IFNbeta). The mechanism of this activation in rheumatoid synovial tissue is unknown."

"This study was designed to investigate the role of the IKK-related kinase IKKepsilon and IFN regulatory factor 3 (IRF-3) in the activation of antiviral genes in rheumatoid arthritis (RA). Kinase assay and...


Source: Virus Weekly (2007-04-10)

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