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Biological Chemistry
New findings in biological chemistry described from Kyoto University, Institute for Virus Research
April 10th, 2007
Current study results from the report, "Viral infections activate types I and III interferon genes through a common mechanism," have been published. "Viral infections trigger innate immune responses, including the production of type I interferons (IFN-alpha and -beta) and other proinflammatory cytokines. Novel antiviral cytokines IFN-lambda1, IFN-lambda2, and IFN-lambda3 are classified as type III IFNs and have evolved independently of type I IFNs," scientists in Kyoto, Japan report. "Type III IFN genes are regulated at the level of transcription and induced by viral infection. Although the regulatory mechanism of type I IFNs is well elucidated, the expression mechanism...
Source: Virus Weekly (2007-04-10)
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