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Chickenpox
Research reports on chickenpox from Stanford University, Department of Pediatrics provide new insights
April 10th, 2007
A new study, "The ubiquitous cellular transcriptional factor USF targets the varicella-zoster virus open reading frame 10 promoter and determines virulence in human skin xenografts in SCIDhu mice in vivo," is now available. According to recent research published in the Journal of Virology, "Varicella-zoster virus (VZV) open reading frame 10 (ORF10) is a determinant of virulence in SCIDhu skin xenografts but not in human T cells in vivo. In this analysis of the regulation of ORF10 transcription, we have identified four ORF10-related transcripts, including a major 1.3-kb RNA spanning ORF10 only and three other read-through transcripts." ...
Source: Virus Weekly (2007-04-10)
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