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Epstein-Barr Virus



Researchers from University of Wisconsin detail findings in Epstein-Barr virus



August 14th, 2007

Investigators publish new data in the report "The plasmid replicon of Epstein-Barr virus: mechanistic insights into efficient, licensed, extrachromosomal replication in human cells." According to a study from the United States, "The genome of Epstein-Barr Virus (EBV) and plasmid derivatives of it are among the most efficient extrachromosomal replicons in mammalian cells. The latent origin of plasmid replication (oriP), when supplied with the viral Epstein-Barr Nuclear Antigen 1 (EBNA1) in trans, provides efficient duplication, partitioning and maintenance of plasmids bearing it."

"In this review, we detail what is known about the viral cis and trans elements required...


Source: Virus Weekly (2007-08-14)

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