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Sendai Virus
Research from University of Geneva yields new findings on sendai virus
August 14th, 2007
A report, "Sendai virus budding in the course of an infection does not require Alix and VPS4A host factors," is newly published data in Virology. "Closing the Sendai virus C protein open reading frames (rSeV-DeltaC virus) results in the production of virus particles with highly reduced infectivity. Besides, the Sendai virus C proteins interact with Alix/AIP1 and Alix suppression negatively affects Sendai virus like particle (VLP) budding," researchers in Geneva, Switzerland report. "Similarly, the Sendai virus M protein has been shown to interact with Alix. On this basis, it has been suggested that Sendai virus budding involves recruitment of the multivesicular...
Source: Virus Weekly (2007-08-14)
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