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West Nile Virus Immunology



Findings from Washington University provide new insights into west nile virus immunology



August 14th, 2007

Investigators publish new data in the report "Antigen-specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis." According to recent research from the United States, "Infection with West Nile virus (WNV) causes fatal encephalitis in immunocompromised animals. Previous studies in mice have established that T cell protection is required for clearance of WNV infection from tissues and preventing viral persistence."

"The current study assessed whether specific WNV peptide epitopes could elicit a cytotoxic T lymphocyte (CTL) response capable of protecting against virus infection. Hidden Markov model analysis was used to identify WNV-encoded...


Source: Virus Weekly (2007-08-14)

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