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West Nile Virus Immunology
Reports from Oregon Health & Science University, Oregon National Primate Research Center advance knowledge in west nile virus immunology
August 14th, 2007
Current study results from the report, "Protective capacity and epitope specificity of CD8(+) T cells responding to lethal West Nile virus infection," have been published. "West Nile virus (WNV) is a small, positive-strand RNA virus belonging to the Flaviviridae genus, which causes lethal encephalitis in a subset of infected birds and mammals. In humans, WNV exhibits pronounced age-related morbidity and mortality, but the basis of this effect is unclear, and the molecular and cellular parameters of the host-WNV infection are just beginning to be elucidated," investigators in the United States report. "Indeed, numerous mechanisms were implicated in protection in vivo...
Source: Virus Weekly (2007-08-14)
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