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Cytomegalovirus Immunology
Research from Medical College of Wisconsin has provided new information about cytomegalovirus immunology
August 14th, 2007
Data detailed in "Human herpesvirus-6A and -6B encode viral immunoevasins that downregulate class I MHC molecules" have been presented. "Like all other members of the herpesvirus family, the closely related human herpesviruses-6 and -7 (HHV-6,7) persist in their host throughout life. In so doing, without exception, every member of the herpesvirus family has evolved mechanisms to avoid detection by the immune system," investigators in the United States report. "In particular, human cytomegalovirus (HCMV), mouse cytomegalovirus (MCMV), human herpesvirus-8 (HHV-8), and herpes simplex virus (HSV) all encode multiple proteins that interfere with proper MHC class I antigen...
Source: Virus Weekly (2007-08-14)
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