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Diabetes Therapy
Reports summarize diabetes therapy study results from Albert Ludwigs University
August 14th, 2007
Fresh data on diabetes are presented in the report "A one-pot chemoenzymatic synthesis for the universal precursor of antidiabetes and antiviral bis-indolylquinones. Bis-indolylquinones represent a class of fungal natural products that display antiretroviral, antidiabetes, or cytotoxic bioactivities. Recent advances in Aspergillus genomic mining efforts have led to the discovery of the tdiA-E-gene cluster, which is the first genetic locus dedicated to bis-indolylquinone biosynthesis," investigators in Freiburg, Germany report. "We have now genetically and biochemically characterized the enzymes TdiA (bis-indolylquinone synthetase) and TdiD (L-tryptophan:phenylpyruvate...
Source: Virus Weekly (2007-08-14)
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