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Gene Therapy
Findings from A. Chopin and co-authors provide new insights into gene therapy
August 14th, 2007
Researchers detail in "KSY1, a lactococcal phage with a T7-like transcription," new data in gene therapy. "The virulent lactococcal phage KSY1 possesses a large elongated capsid (223 nm long, 45 nm wide) and a short tail (32 nm). This phage of the Podoviridae group (C3 morphotype) has a linear 79,232-bp double-stranded DNA genome, which encodes 131 putative proteins and 3 tRNAs," scientists in Jouy-en-Josas, France report. "This is the first description of the genome of a phage of this morphotype. KSY1 possesses a T7-like transcription system, including an RNA polymerase and a series of specific promoters, showing sequence homology to other known T7-like RNA polymerase...
Source: Virus Weekly (2007-08-14)
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