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Gene Therapy



Findings from Massachusetts Institute of Technology broaden understanding of gene therapy



August 14th, 2007

New investigation results, "Non-viral siRNA delivery to the lung," are detailed in a study published in Advanced Drug Delivery Reviews. "SiRNAs exert their biological effect by guiding the degradation of their cognate mRNA sequence, thereby shutting down the corresponding protein production (gene silencing by RNA interference or RNAi). Due to this property, siRNAs are emerging as promising therapeutic agents for the treatment of inherited and acquired diseases, as well as research tools for the elucidation of gene function in both health and disease," scientists in the United States report.

"Because of their lethality and prevalence, lung diseases have attracted...


Source: Virus Weekly (2007-08-14)

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