West Nile Virus
Reports from University of Texas describe recent advances in west nile virus
Published in Virus Weekly, March 4th, 2008
According to recent research from the United States, "Dendritic cells (DCs) play a central role in innate immunity and antiviral responses. In this study, we investigated the production of alpha interferon (IFN-alpha) and inducible chemokines by human monocyte-derived dendritic cells (mDCs) and plasmacytoid dendritic cells (pDCs) infected with West Nile virus (WNV), an emergent pathogen whose infection can lead to severe cases of encephalitis in the elderly, children, and immunocompromised individuals."
"Our experiments demonstrated that WNV grown in mammalian cells (WNVVero) was a potent inducer of IFN-alpha secretion in pDCs and, to a lesser degree, in mDCs. The...
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Source: Virus Weekly (2008-03-04)
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