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HIV/AIDS Co-Infection

Recent studies from Yeshiva University, Medical Department add new data to HIV/AIDS co-infection

Published in Virus Weekly, June 3rd, 2008

According to a study from the United States, "The human immunodeficiency virus type I (HIV-1)-specific CD8 cytotoxic T-lymphocyte (CTL) response plays a critical role in controlling HIV-1 replication. Augmenting this response should enhance control of HIV-1 replication and stabilize or improve the clinical course of the disease."

"Although cytomegalovirus (CMV) or Epstein-Barr virus (EBV) infection in immunocompromised patients can be treated by adoptive transfer of ex vivo-expanded CMV- or EBV-specific CTLs, adoptive transfer of ex vivo-expanded, autologous HIV-1-specific CTLs had minimal effects on HIV-1 replication, likely a consequence of the inherently compromised...

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