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Virus Weekly

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Asthma



New data from University of London, Imperial College illuminate research in asthma



November 25th, 2008

According to a study from London, the United Kingdom, "Acute exacerbations are the major cause of asthma morbidity, mortality, and health-care costs and are difficult to treat and prevent. The majority of asthma exacerbations are associated with rhinovirus (RV) infection, but evidence supporting a causal relationship is weak and mechanisms are poorly understood."

"We hypothesized that in asthmatic, but not normal, subjects RV infection would induce clinical, physiologic, and pathologic lower airway responses typical of an asthma exacerbation and that these changes would be related to virus replication and impaired T helper 1 (Thl)/IL-10 or augmented Th2 immune...


Source: Virus Weekly (2008-11-25)

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