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Salk Institute
Newborn neurons in the adult brain can settle in the wrong neighborhood
November 25th, 2008
In a study that could have significant consequences for neural tissue transplantation strategies, researchers at the Salk Institute for Biological Studies report that inactivating a specific gene in adult neural stem cells makes nerve cells emerging from those precursors form connections in the wrong part of the adult brain. In a paper published in the Nov. 11 issue of PLoS Biology, the team, led by Fred H. Gage, Ph.D., professor in the Laboratory of Genetics, discovered that a protein called cdk5 is necessary for both correct elaboration of highly branched and complex antennae, known as dendrites, which are extended by neurons, and the proper migration of cells bearing...
Source: Virus Weekly (2008-11-25)
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