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Sendai Virus



Studies from Aarhus University reveal new findings on sendai virus



June 16th, 2009

"The innate immune system provides an initial defense system against microbial infections and contributes to the development of adaptive immune response. Type I interferons play a pivotal role for the first line of defense against virus infections, and dendritic cells (DCs) are important sensors of pathogens responsible for priming of adaptive immune responses in lymphoid organs," researchers in Aarhus, Denmark report.

"Here we have investigated the role and mechanisms of activation of the MAPK pathway in innate immune responses induced by Sendai virus, a negative sense single-stranded RNA virus. Both p38 and JNK were activated in fibroblasts and DCs after infection...


Source: Virus Weekly (2009-06-16)

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