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Arthritis

Research on arthritis published by scientists at Charite University

Published in Virus Weekly, August 4th, 2009

"Analysis of the histopathologic features of hip arthritis in patients with ankylosing spondylitis (AS) has revealed accumulation of infiltrating mononuclear cells in the bone end plate and presence of hyaline articular cartilage that is not found in areas of total cartilage destruction. This study was undertaken to assess whether chondrocytes attract lymphocytes and whether cartilage chondrocytes from patients with AS have the potential to directly stimulate T cells in an HLA-restricted manner," scientists in Berlin, Germany report.

"Human HLA-B27+ T cell lines, specific for the Epstein-Barr virus-derived peptide EBNA(258-266), and autologous chondrocytes, serving as...

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