Bladder Cancer

Scientists at University of Texas detail research in bladder cancer

Published in Virus Weekly, September 29th, 2009

"The epithelial-to-mesenchymal transition (EMT) is a cell development-regulated process in which noncoding RNAs act as crucial modulators. Recent studies have implied that EMT may contribute to resistance to epidermal growth factor receptor (EGFR)-directed therapy," scientists writing in the journal Clinical Cancer Research report.

"The aims of this study were to determine the potential role of microRNAs (miRNA) in controlling EMT and the role of EMT in inducing the sensitivity of human bladder cancer cells to the inhibitory effects of the anti-EGFR therapy. miRNA array screening and real-time reverse transcription-PCR were used to identify and validate the...

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Source: Virus Weekly (2009-09-29)

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