Influenza
Research from M.R. Sandbulte and co-researchers provides new data on influenza
Published in Virus Weekly, October 6th, 2009
"Antibodies to neuraminidase (NA) contribute to protection during influenza virus infection, but NA inhibition (NI) titers are not routinely analyzed in vaccine trials. One reason is the cumbersome nature of the conventional thiobarbituric acid (TBA) NI assay, which uses chemical methods to quantify free sialic acid following incubation of NA with substrate in the presence of serum," scientists in the United States report.
"In addition, the assay is complicated by the need to use virus of a hemagglutinin (HA) subtype novel to the host to detect NA-specific antibodies only. Our primary objectives were to miniaturize the colorimetric NI assay to a format suitable for...
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Source: Virus Weekly (2009-10-06)
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