Molecular Immunology
Data from Leiden University Medical Center Provide New Insights into Molecular Immunology
Published in Virus Weekly, April 5th, 2011
2011 APR 5 -- A report, 'Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses,' is newly published data in Molecular Immunology. "Herpesviruses escape elimination by cytotoxic T lymphocytes through specific interference with the antigen-presenting function of MHC class I (MHC I) molecules. The transporter associated with antigen processing (TAP) forms a bottleneck in the MHC I antigen presentation pathway," researchers in Leiden, Netherlands report.
"The fact that multiple viruses, especially herpesviruses, encode molecules blocking TAP function is a case in point. The action of these viral immuno evasins is usually...
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Source: Virus Weekly (2011-04-05)
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