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U.S. Centers for Disease Control & Prevention

Exfoliated cervical cells may yield RNA for biomarker discovery

Published in Women's Health Law Weekly, May 9th, 2004

Exfoliated cervical cells may yield RNA for molecular epidemiology and biomarker discovery.

"The biologic sample collected in molecular epidemiology studies must accurately reflect the disease being studied and have sufficient molecular quality for the intended assays. Noninvasive sampling methods, such as scrapes or brushes, are increasingly used. In this study, we evaluate the impact of sample collection media and extraction methods on the quality and yield of RNA from routine exfoliated cervical cytology," scientists in the United States report.

"Excess cellular material remaining on the cytologic collection device after preparation of the routine...

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