Edouard Herriot Hospital, Lyon

Study: BMD only partly defines structural basis of fracture risk reduction

Published in Women's Health Law Weekly, June 27th, 2004

Researchers in France say that changes in bone mineral density aren't the end of the story when it comes to understanding the structural basis of fracture risk reduction in patients on anti-resorptive therapy.

"The structural basis for the reduction in vertebral and nonvertebral fracture risk in patients using anti-resorptive therapy is not well understood. As reduced bone mineral density (BMD) increases the risk for fracture and anti-resorptive agents increase BMD, it was commonly held that the increase in BMD explained the fracture risk reduction, until several meta-analyses either failed to detect a significant association between vertebral fracture risk reduction...

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Source: Women's Health Law Weekly (2004-06-27)

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