AFSSA Paris, Maisons Alfort
Continuous factor-dependent pig mast cell line developed from fetal progenitors
Published in Women's Health Law Weekly, September 4th, 2005
"Mast cells (MCs) are tissue resident, hematopoietic stem cells-derived elements, distributed throughout the body. They are the pivotal mediating cells of allergic reactions. In addition, in mice, MCs play a critical role in the defense against several pathogens, such as bacteria, parasites and viruses.
"Whereas the biology of rodent and human MCs has been extensively studied using in vitro derived populations, the role of MCs in pigs has not yet been evaluated, given the very low availability of pure porcine MCs populations," investigators in France...
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