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Columbia Presbyterian Medical Center, New York

Angiogenic growth factors may attenuate erectile dysfunction in the rat penis

Published in Women's Health Law Weekly, November 27th, 2005

Angiogenic growth factors may attenuate erectile dysfunction (ED) in the rat penis.

Scientists in the United States conducted research "to establish a laboratory animal model for vascular endothelial growth factor (VEGF) transfer in the rat penis to invent a curative therapy for ED. Vascular insufficiency is a common pathomechanism of ED."

"Previous investigations have shown neovascularization of ischemic organs after gene transfer of VEGF. For VEGF-protein transfer, osmotic pumps were connected to the renal arteries of rats. The pumps were filled with human VEGF165 protein (n=20) or sterile saline (n=20). After 28 days, a VEGF serum...

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