Women's Health Law Weekly
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Free & Humboldt University of Berlin
Expression levels of LIV-1 were associated with better outcome in breast cancer
February 5th, 2006
Expression levels of LIV-1 were associated with a better outcome in breast cancer. "We investigated the expression pattern of the breast cancer associated gene LIV-1 on all and protein level in 111 human breast cancer patients by in situ hybridization as well as immunohistochemistry and focused on the unknown potential of LIV-1 expression levels as a prognostic marker. To our knowledge, this is the first study on endogenous LIV-1 protein expression," investigators in Germany reported. "Results of our study indicate that LIV-1 mRNA and protein expression levels are only weakly correlated, suggesting posttranscriptional regulatory mechanisms....
Source: Women's Health Law Weekly (2006-02-05)
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