Women's Health Law Weekly
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John Radcliffe Hospital, Oxford
The 16189 mitochondrial DNA variant is linked to thinness in mothers and their offspring
February 5th, 2006
The 16189 mitochondrial DNA variant is associated with thinness in mothers and their 20-yr-old offspring. "A common mitochondrial (mt) DNA variant that is maternally inherited, the 16189 variant, is associated with type 2 diabetes and thinness at birth. To elucidate the association of the variant with thinness, we studied the 16189 variant in a well-characterized Australian cohort (n=161) who were followed up from birth to age 20 yr," investigators in England report. E. Parker and colleagues at John Radcliffe Hospital explained, "PCR analysis and mtDNA haplotyping was carried out on DNA from 161 offspring from consecutive, normal, singleton...
Source: Women's Health Law Weekly (2006-02-05)
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