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Women's Health Law Weekly

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Fred Hutchinson Cancer Research Center, Seattle



Recent findings in HIV/AIDS pathogenesis provide new insights



February 5th, 2006

HIV/AIDS pathogenesis research advances have been reported from the United States and South Africa.

Study 1: Cytotoxic T lymphocytes can kill, on average, 0.7 to 3 HIV-infected target cells per day.

"The antiviral role of CD8+ cytotoxic T lymphocytes (CTLs) in human immunodeficiency virus type 1 (HIV-1) infection is poorly understood. Specifically, the degree to which CTLs reduce viral replication by killing HIV-1-infected cells in vivo is not known," scientists in the United States report.

"Here we employ mathematical models of the infection process and CTL action to estimate the rate that CTLs can kill HIV-1-infected cells from...


Source: Women's Health Law Weekly (2006-02-05)

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