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Women's Health Law Weekly

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Chiang Mai University



Long-term zidovudine prophylaxis reduces HIV-1 vertical transmission to neonates



February 5th, 2006

Long-term zidovudine prophylaxis reduces HIV-1 vertical transmission to neonates.

According to scientists in Thailand, "Antiretroviral treatment with zidovudine (ZDV) from the 14th week until the end of pregnancy has markedly reduced the vertical transmission rate of HIV-1 in Europe and North America." "A shorter duration of treatment has reduced this rate in Africa and Southeast Asia to a lesser degree. In Southeast Asia, subtype E is the major subtype rather than subtype B as in Western countries. The goals of this study were to determine the optimal duration of ZDV prophylaxis for subtype E and to confirm its effectiveness at the histologic level."

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Source: Women's Health Law Weekly (2006-02-05)

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